Editorial: Persistent endeavors for the enhancement of dissolution and oral bioavailability

toxicity evaluation of microemulsion (nano size) of sour cherry kernel extract for the oral bioavailability enhancement

background: in the recent years nanostructured materials have been the focus of researches due to their wide-spread possibilities to provide new shapes and structures for some materials. microemulsions can provide uniform nano-sized droplets for templating. microemulsions are isotropic, thermodynamically-stable systems of oil, water and surfactant with a 20-200 nm droplet size. they can be prep...

Nanoprecipitation with sonication for enhancement of oral bioavailability of furosemide.

Furosemide is a weakly acidic diuretic indicated for treatment of edema and hypertension. It has very poor solubility but high permeability through stomach and upper gastrointestinal tract (GIT). Due to its limited solubility it has poor and variable oral bioavailibility of 10-90%. The aim of this study was to enhance the oral bioavailibilty of furosemide by preparation of nanosuspensions. The ...

Rosuvastatin Loaded Nanostructured Lipid Carrier: For Enhancement of Oral Bioavailability

Rosuvastatin is a lipid lowering agent, which has low solubility and low bioavailability of 20% with oral administration. Therefore the present study was undertaken to improve solubility and bioavailability of Rosuvastatin by formulating it into Nano structured lipid carriers (NLCs) by using stearic acid and Compritol ATO 888 as solid-lipid, Oleic acid as liquid-lipid and Poloxamer 188 as a sur...

The use of spray freeze drying for dissolution and oral bioavailability improvement of Azithromycin

assessment of the effect of honey as a topical therapy for intra oral wound healing in rat.

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